Is CBD the perfect compound to fight migraine? All about its potential against this disorder

In recent years, interest in the use of medical marijuana and CBD as medical alternatives has been high.

Research on the impact of cannabis on migraines has been limited, but promising studies were recently conducted at the American Headache Society Annual Meeting.

What is migraine?

Migraines are a common neurological disorder that affects millions of people worldwide. In the United States, approximately 47 million people suffer from migraines, and 75% of them are women.

Migraine symptoms are debilitating and include throbbing headache pain, visual disturbances, nausea, sensitivity to light and sound, brain fog and severe pain.

Given the significant impact migraines have on the quality of life of migraine sufferers, it is crucial to seek effective and safe treatments. The study on the use of vaporized cannabis as a treatment for migraines offers a new perspective and hope for those seeking relief.

What supports the effectiveness of cannabis against migraine?

Dr. Nathaniel Schuster, a headache specialist at the University of San Diego Pain Treatment Center, presented data from a clinical trial at the 2023 Annual Meeting of the American Headache Society. This study was a double-blind, placebo-controlled, randomized trial investigating the use of vaporized cannabis as a potential treatment for migraines.

In the study, patients were randomly assigned to one of the following groups: THC, a mixture of THC and CBD, CBD, and placebo. The results were promising, as a decrease in headaches and the most bothersome symptoms was observed within two hours of administration of a THC and CBD combination. Furthermore, no dose-dependent effect was observed, indicating that even low amounts of cannabis can be effective in treating migraines.

What is the recommended dose of cannabis to treat migraine?

Although the study showed promising results, Dr. Schuster cautions that marijuana may be too strong for some patients. Especially for those who live in areas where marijuana use is legal and have access to strains with high THC levels. In these cases, it is important to experiment with lower doses to avoid unwanted effects, such as hyperalgesic effects or increased pain concentration.

Don’t forget that the use of cannabis to treat migraines should be guided by a healthcare professional. The doctor will be able to assess your needs and tolerance to these compounds, and will also recommend the appropriate dose and the most convenient form of administration for you.


The presented study demonstrates the incredible potential of CBD and THC to treat migraines. Results obtained support the efficacy of vaporized cannabis in reducing headaches and the most bothersome symptoms within two hours of administration. Furthermore, low doses of cannabis were found to be equally effective as higher doses.

Undoubtedly, CBD and THC offer a promising alternative to combat migraines and their bothersome symptoms. As more research is conducted in this field, new ways of using cannabis safely and effectively in the relief of this common neurological disorder may be discovered.